Creatine is similar to protein in that it is a nitrogen-containing compound, but is not a true protein. In the nutritional biochemistry world it is known as a “non-protein” nitrogen. It can be obtained in the food we eat (typically meat and fish) or formed endogenously (in the body) from the amino acids glycine, arginine, and methionine.
Chemical Name:Creatine monohydrate
Other name:Creatine;N-Amidinosarcosine
CAS No.:6020-87-7
Molecular formula:C4H11N3O3
Chemical structure:200mesh or 80mesh Creatine Monohydrate powder
EINECS No.:200-306-6
COA
How does it works?
Creatine is a key player in the phosphagen energy system, the primary source of ATP (the main energy substrate in our body) during short-term, high intensity activities. Creatine exists as both free form creatine and phosphocreatine in the body. Phosphocreatine (PC) functions as a “storehouse for high energy phosphate”2.
PC functions to replenish ATP in muscles that are rapidly contracting by transferring a phosphate group to the ADP that was formed from the hydrolysis of ATP for energy in the contracting muscle. When our muscles run out of creatine, our short-term, high intensity energy system shuts down and our muscles are no longer able to produce force.
The use of creatine as an ergogenic aid is based upon the theory that one can increase the saturation of creatine in the muscle through supplementation. This is an important point which we will discuss in a section below.
Theoretically, increased creatine in the muscle will increase performance in short, high intensity exercise by increasing the capacity of our phosphagen system.
Benefits
Creatine is one of the most widely researched supplements. In fact, a google scholar search for the terms “creatine supplemenation” yielded 6,740 scholarly articles and a PubMed search yielded 562 articles, indicating there is a plethora of data for us to draw conclusions from. From decades of research and hundreds of studies, there are several well substantiated benefits to creatine monohydrate including:
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