Ginseng, a kind of perennial herbaceous plant, florescence is from June to September, fruit period is from July to Sepetember. Wild species always founded in Northeast China, Changbai Mountains and the South-east zone of Xiaoxing’anling. Liaoning, Jilin and Heilongjiang provinces have a large number of cultivation. In addition, Hebei, Shanxi, Shaanxi, Inner Mongolia and other province have aslo introduced this plant.

Ginseng extract is typically derived from the root and leaves of this plant. As an herbal supplement, the extract has long been prized for its reputation of having anti-inflammatory, anti-cancer, et des propriétés antioxydantes. It is also used in the homeopathic treatment of conditions, including depression, stress, low libido, and attention deficit hyperactivity disorder. It contains vitamins A and B-6, which aids in the production of thymic hormones, necessary for the functioning of the defense system.

Ginsenoside F2 is a triterpene saponin originally found in species of Panax that exhibits anti-obesity and anticancer chemotherapeutic activities. Ginsenoside F2 inhibits hair cell apoptosis, decreasing expression of TGF-β2, SCAP, and SREBP in vivo. Ginsenoside F2 also decreases lipid accumulation in adipocytes, suppressing expressing of PPARγ and perilipin and inhibiting adipogenesis. This compound also induces formation of acidic vesicles, autophagy, and mitochondrial apoptosis in breast cancer stem cells; additionally, it decreases tumor growth in animal models of glioblastoma.

Ginsenoside F2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 et 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position. It has a role as an apoptosis inducer, an antineoplastic agent and a plant metabolite. It is a ginsenoside, a tetracyclic triterpenoid, a 12beta-hydroxy steroid and a beta-D-glucoside.

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