Genistein Details
Product Name: Genistein
Herb Source: Rhizome of Genista tinctoria Linn and Sophora subprostrata Chun et T.Chen., Fruit of Sophora japonica L.
Part Used: Rhizome, Root
Appearance: Greyish-white Powder
Specification: 98%
Test Method: HPLC
CAS#: 446-72-0
Molecular Weight & Molecular Formula: C15H10O5; 270.25
Genistein Structural Formula:
Melting Point & Solubility: mp297℃-298℃, Soluble in DMSO, ethanol and the usual organic solvents, in dil alkalies with yellow color. Practically insol in water.
Pharmacology: Anti-carcinogenic activity; anti-oxidant activity; anti-atherosclerosis; functions as Estrogen; reducing Cholesterol and triglyceride Levels; preventing osteoporosis.
What Is Genistein?
Genistein is a variety of isoflavone which is most active, it is extracted from dry and mature fruit of soybean plant sophora Japonica. It is a pure and single element. It is a compound of heterocycle polyphenol. Genistein is frequently found with the isoflavone daidzein, and together they are considered soy isoflavones.
Genistein can combine with estrogen receptor and have weak estrogen effect. So it is also called phytoestrogen. Genistein is antagonistic to estrogen. It has protective effect or hormone related diseases. Genistein powder can improve and prevent climacteric syndrome and osteoporosis. It can serve as food supplement to be widely used in various healthy food for the middle-aged and old people.
Genistein powder binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.
Main Functions And Benefits Of Genistein
1. Genistein can bind to estrogen receptors, play a weak estrogen-like effects, increas bone density, and prevent bone loss, to treat osteoporosis.
2. Genistein powder has certain anticancer effect, can kill various cancer cells without damaging the normal cells.
3. Genistein have anti-peroxidation activity, can increase the activity of low density lipoprotein receptor, reduce cholesterol levels, accelerated cholesterol removal, to reduce plasma lipid and anti-thrombosis.
4. Genistein has therapeutic potential against liver fibrosis by regulating PDGF and TGFβ1.
Application Of Genistein
1. Applied in the field of pharmaceutical as raw material, genistin can be made into suppositories, lotions, injection, tablets, capsules and so on.
2. Applied in the field of health care products and supplement field as raw material, genistein powder can be used as beauty care products for women and also it can prevent blood diseases and cancer.
3. Genistin can be used in food field.
4. Genistin can be used in cosmetic field.
IMAHERB BIOTECH is one of the professional and credible top quality Genistein for sale manufacturers, who is dedicated to produce the top quality organic products which is of great benefits to customers. If you want to know how to buy such products, welcome to contact us and we will offer you the best price.
IMAHERB BIOTECH is one of the professional and credible top quality Genistein for sale manufacturers, who is dedicated to produce the top quality organic products which is of great benefits to customers. If you want to know how to buy such products, welcome to contact us and we will offer you the best price.