Imaherb Factory supply 4-Butylresorcinol Powder CAS 18979-61-8

Product information

Imaherb Factory supply 4-Butylresorcinol Powder CAS 18979-61-8

The official chemical name is 4-n-butyl resorcinol, but generally, everyone likes to simplify writing butyl resorcinol. The first one to add to the whitening product is the Japanese POLA, um~ the one that relies on the whitening pill in the domestic fire.

It is characterized by poor solubility in water and soluble in ethanol.

Why you should choose 4-Butylresorcinol

First, we need to know why there is resorcinol.

Lipofuscin is one of the more difficult to deal with in melanin. In general, hydroquinone is used in medical beauty.

Hydroquinone is a very effective whitening agent. The whitening mechanism completely inhibits the activity of tyrosinase and prevents the formation of melanin, and the effect is very remarkable.

However, its side effects are equally obvious, and the benefits are much more harmful than the benefits of whitening.

• It is highly oxidizable in the air, and it must be used when adding it to cosmetics.
• can cause redness of the skin;
• If the concentration exceeds 5%, it will cause sensitization, and there are clinical examples of leukoplakia. Currently, the US Food and Drug Administration stipulates that hydroquinone products with a concentration greater than 4% are medical grade and are not allowed to be marketed.

Chemists and pharmacists have modified the potent drug hydroquinone to get 4-hydroxyphenyl-beta-D-glucopyranoside, which is what we often hear about as “arbutin”. The difference between hydroquinone is that arbutin has a small tail – glycoside than hydroquinone. It is a pity that the whitening effect is greatly reduced.

In recent years, the most popular ingredients of major brands are various derivatives of benzenediol.

But light stability of arbutin is very poor and only effective at night.
The safety of 4-n-butyl resorcinol has become a prominent highlight. Without the side effects of hydroquinone, it has a better curative effect than other resorcinol derivatives.
In the tyrosinase activity inhibition experiment, its data is even better than the big brother phenethyl resorcinol, which is 100~6000 times of the traditional whitening agent such as kojic acid arbutin!
Then in the subsequent advanced experimental melanin B16V, also showed a common advantage of resorcinol derivatives – inhibition of melanin production at concentrations that did not produce cytotoxicity.

In addition, there are many human experiments on 4-n-butyl resorcinol. In some 32 patients with chloasma, 0.3% 4-n-butylresorcinol and placebo were used on both cheeks. Twice a day for 3 months, the result was a significantly lower pigment reduction in the 4-n-butylresorcinol group than in the placebo group. There are people who do artificial pigmentation inhibition experiments after artificial sunburn, hmm~ the result is of course quite good Inhibition of human tyrosinase by 4-butylresorcinol.

Dosage and usage of 4-Butylresorcinol

The recommended dosage is 0.5%-5%. Although there are studies in Korea that have a certain effect on 0.1% cream, India has researched 0.3% cream but the market is mainly 0.5%-5%. It is more common, and the Japanese formula is still unclear, but POLA has been used. And the results and sales are quite impressive.

Packing and Shipping

FAQ 

Imaherb Factory supply Health Supplement Zinc Orotate CAS 68399-76-8

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