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D-Pinitol/CAS NO.10284-63-6

2018-04-17

What is D-Pinitol

D-pinitol is a naturally occuring compound that can be found in some plants, trees,and food, such as soy.D-pinitol has demonstrated effects similar to insulin that drive creatine and other nutrients into the muscles.D-pinitol is a methyl-inositol extract that promotes the transport of glucose and glycogen synthesis. D-pinitol is often combined with creatine and a small amount of carbohydrates.

Major effects:Concretion run smoothly, eliminating phlegm to disappear unless cough. Have stimulated insulin ability, can reduce blood sugar. Can promote creative absorption, often as a creatine product additive.

       

D-Pinitol, an anti-diabetic substance, is a naturally occurring compound found in legumes. In this study, we investigated the inhibitory effect of D-pinitol on growth and recurrence of breast cancer. When D-pinitol was treated on MDA-MB- 231 or MCF-7 breast cancer cells, it was observed that the viability of the two cancer cell lines was reduced in MTT assay. In order to examine the effect on the growth of breast tumor, mouse xenograft assay was carried out. On day 0, nine millions cells of MDA-MB-231 were injected subcutaneously into nude mouse and D-pinitol was administered orally at the dose of 500 mg/kg or 1000 mg/kg body weight for consecutive 45 days. Tumor size was reduced in dose-dependent manner upto 95.4% in 1000 mpk-treated group, compared with the non-treated control group. When D-pinitol was co-administrated with 4 渭g of doxorubicin, recurrence of breast tumor was delayed by two weeks, compared with the mouse group of doxorubicin monotherapy. Consistent with this data, it was observed that the population of cancer stem cells (CSCs), responsible for recurrence of cancer, within tumor mass was significantly reduced. Taken together, D-pinitol inhibits the growth of breast cancer and relapse of the tumor by suppressing the proliferation of CSCs.

About Our D-Pinitol

Product name: D-Pinitol
Specification: 95%
CAS NO.: 10284-63-6
Appearance: White powder
Particle Size: 90% pass through 80 mesh sieve
Test method: HPLC
Extract Solvent: Ethanol & WaterUsage: Pharmaceuticals, healthcares, and cosmetics.

Function Of D-Pinitol

1. Prevention of aging-related macular degeneration (the leading cause of blindness in the elderly);
2. To prevent cataracts, intima-media thickening, heart disease;
3. To improve the symptoms in patients with retinitis pigmentosa;
4. Reduce the color difference, so that vision is more precise; the protection of the retina, when the absorption of light from oxidative damage;
5. Anticarcinogenic effect and prevent the proliferation of cancer cells.

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