Climbazole (CAS 38083-17-9) is a broad-spectrum antifungal active widely used in anti-dandruff and scalp-care products. It targets Malassezia — the yeast most associated with dandruff — while being gentle enough for daily-use shampoos and conditioners.
Physical & Chemical Properties
- INCI: Climbazole
- CAS number: 38083-17-9
- Appearance: white to off-white crystalline powder
- Solubility: slightly soluble in water; soluble in ethanol and most organic solvents
- Molecular formula: C15H17ClN2O2
- Ionic type: azole antifungal, non-ionic
- Melting point: approx. 146–148°C
Key Benefits for Formulation
- Anti-dandruff efficacy: inhibits Malassezia growth at low use levels
- Broad-spectrum antifungal: effective against common scalp fungi
- Gentle profile: suitable for daily anti-dandruff shampoos
- Formulation flexible: works in clear and pearlized shampoos
- Proven ingredient: decades of use in OTC scalp care
Main Applications
- Anti-dandruff shampoos: daily and treatment formats
- Scalp care lotions & tonics: leave-on anti-itch care
- Conditioners & treatments: dandruff prevention
- Cleansing bars & gels: medicated-style cleansing
- Pet care: antifungal skin care formulations
Why Choose Our Bulk Climbazole?
- GMP manufacturing: full quality control from raw material to finished product
- Complete documentation: COA, SDS and heavy metal test reports available on request
- Flexible supply: MOQ and lead time on inquiry, from R&D samples to mass production
- Export experience: reliable shipping to EU, North America, Australia and Middle East
Recommended Usage
Typical use level 0.5%–1% in rinse-off anti-dandruff products; lower levels in leave-on formats. Always confirm local regulatory limits for your target market.
FAQ About Wholesale Climbazole
What is the CAS number of Climbazole?
CAS 38083-17-9.
What is the INCI name?
Climbazole.
How does Climbazole work against dandruff?
It inhibits the growth of Malassezia yeast, the primary microbial cause of dandruff and scalp itching.
Is Climbazole soluble in water?
It is slightly soluble in water and soluble in ethanol and most organic solvents — typically predisposed in the surfactant or alcohol phase.
What is the recommended use level?
0.5%–1% in rinse-off anti-dandruff products; lower in leave-on formats.
Is it suitable for daily-use shampoos?
Yes — it is gentle enough for daily anti-dandruff formulations.
Is Climbazole approved in the EU/US?
It is an established anti-dandruff active in many regions; always verify local cosmetic regulations for your market.
Can it be combined with Zinc Pyrithione or Piroctone Olamine?
Yes — combinations are common in multi-active anti-dandruff systems; run stability testing.
Start Your Climbazole Bulk Order
Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.