Rhein (CAS 478-43-3) is a natural anthraquinone found in rhubarb (Rheum species) and senna. It is widely studied for anti-inflammatory, antioxidant and metabolic-health activities, and supplied as a high-purity reference and research compound.
Physical & Chemical Properties
- INCI: Rheum Palmatum Root Extract / Rhein
- CAS number: 478-43-3
- Appearance: yellow to orange-yellow powder
- Solubility: soluble in DMSO and alkaline solutions; sparingly soluble in water
- Molecular formula: C15H8O6
- Molecular weight: 284.22
- Source: Rheum palmatum / Rheum officinale root
- Purity: HPLC ≥98%
Key Benefits for Formulation
- Anti-inflammatory research: one of the most studied rhubarb anthraquinones
- Antioxidant activity: free-radical scavenging
- Metabolic-health studies: growing research interest
- High purity: HPLC ≥98% for reproducible studies
- Natural origin: plant-derived compound
Main Applications
- Research compounds: anti-inflammatory and metabolic studies
- Dietary supplement research: botanical anthraquinone applications
- Herbal standardization: rhubarb marker compound
- Cosmetic research: antioxidant actives
- Pharmaceutical reference: analytical standards
Why Choose Our Bulk Rhein?
- GMP manufacturing: full quality control from raw material to finished product
- Complete documentation: COA, SDS and heavy metal test reports available on request
- Flexible supply: multiple HPLC purity grades in stock, from R&D samples to mass production
- Export experience: reliable shipping to EU, North America, Australia and Middle East
Recommended Usage
Research and supplement use as directed by protocols. For internal study only in many jurisdictions — confirm regulatory status for commercial use.
FAQ About Wholesale Rhein
What is the CAS number of Rhein?
CAS 478-43-3.
What is Rhein?
A natural anthraquinone from rhubarb (Rheum species) and senna.
What purity is available?
HPLC ≥98%.
Is Rhein water soluble?
It is sparingly soluble in water; soluble in DMSO and alkaline solutions.
What is it used for?
Anti-inflammatory, antioxidant and metabolic-health research, plus rhubarb standardization.
Is it the same as emodin?
No — Rhein and emodin are different anthraquinones found in rhubarb.
Do you provide COA and SDS?
Yes — COA, SDS and heavy metal test reports are available on request.
What is the shelf life?
Typically 24 months stored sealed in a cool, dry place.
Can I get samples?
Yes — trial samples available; terms negotiable with bulk orders.
What are your MOQ terms?
Flexible MOQ, discussed on inquiry.
Start Your Rhein Bulk Order
Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.