Licochalcone A (CAS 58749-22-7) is a chalcone from licorice root celebrated for its anti-inflammatory, anti-acne and soothing properties. It calms redness, supports acne-prone skin and is a hero active in dermo-cosmetic calming lines — available in multiple HPLC grades.
Physical & Chemical Properties
- INCI: Glycyrrhiza Inflata Root Extract / Licochalcone A
- CAS number: 58749-22-7
- Appearance: yellow to orange-yellow powder
- Solubility: soluble in ethanol, methanol and DMSO; sparingly soluble in water
- Molecular formula: C21H22O4
- Molecular weight: 338.40
- Source: Glycyrrhiza inflata root
- Purity: HPLC 10%–98% multi-grade
Key Benefits for Formulation
- Anti-inflammatory: calms redness and irritation
- Anti-acne: supports acne-prone skin care
- Soothing: ideal for sensitive skin formulas
- Multi-grade: 10%–98% to fit cost and claim targets
- Dermo-cosmetic standard: proven in calming care lines
Main Applications
- Soothing creams & lotions: redness-calming care
- Anti-acne products: blemish and irritation control
- Sensitive-skin care: gentle daily formulas
- After-shave & post-procedure: calming applications
- Serums & ampoules: concentrated soothing actives
Why Choose Our Bulk Licochalcone A?
- GMP manufacturing: full quality control from raw material to finished product
- Complete documentation: COA, SDS and heavy metal test reports available on request
- Flexible supply: multiple HPLC purity grades in stock, from R&D samples to mass production
- Export experience: reliable shipping to EU, North America, Australia and Middle East
Recommended Usage
Typical use level 0.01%–0.5% in soothing and anti-acne formulas, depending on grade and target efficacy.
FAQ About Wholesale Licochalcone A
What is the CAS number of Licochalcone A?
CAS 58749-22-7.
What is Licochalcone A?
A chalcone from licorice (Glycyrrhiza inflata) root with anti-inflammatory and anti-acne activity.
What purity grades are available?
HPLC 10%, 30%, 50%, 90%, 95%, 98% available in stock.
Is it water soluble?
It is sparingly soluble in water; soluble in ethanol, methanol and DMSO.
What is the recommended use level?
0.01%–0.5% in soothing and anti-acne formulations.
Is it suitable for acne-prone skin?
Yes — it is known for anti-acne and calming benefits.
Do you provide COA and SDS?
Yes — COA, SDS and heavy metal test reports are available on request.
What is the shelf life?
Typically 24 months stored sealed in a cool, dry place.
Can I get samples?
Yes — trial samples available; terms negotiable with bulk orders.
What are your MOQ terms?
Flexible MOQ, discussed on inquiry.
Start Your Licochalcone A Bulk Order
Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.