Description

Licochalcone A (CAS 58749-22-7) is a chalcone from licorice root celebrated for its anti-inflammatory, anti-acne and soothing properties. It calms redness, supports acne-prone skin and is a hero active in dermo-cosmetic calming lines — available in multiple HPLC grades.

Physical & Chemical Properties

• INCI: Glycyrrhiza Inflata Root Extract / Licochalcone A
• CAS number: 58749-22-7
• Appearance: yellow to orange-yellow powder
• Solubility: soluble in ethanol, methanol and DMSO; sparingly soluble in water
• Molecular formula: C21H22O4
• Molecular weight: 338.40
• Source: Glycyrrhiza inflata root
• Purity: HPLC 10%–98% multi-grade

Key Benefits for Formulation

• Anti-inflammatory: calms redness and irritation
• Anti-acne: supports acne-prone skin care
• Soothing: ideal for sensitive skin formulas
• Multi-grade: 10%–98% to fit cost and claim targets
• Dermo-cosmetic standard: proven in calming care lines

Main Applications

• Soothing creams & lotions: redness-calming care
• Anti-acne products: blemish and irritation control
• Sensitive-skin care: gentle daily formulas
• After-shave & post-procedure: calming applications
• Serums & ampoules: concentrated soothing actives

Why Choose Our Bulk Licochalcone A?

• GMP manufacturing: full quality control from raw material to finished product
• Complete documentation: COA, SDS and heavy metal test reports available on request
• Flexible supply: multiple HPLC purity grades in stock, from R&D samples to mass production
• Export experience: reliable shipping to EU, North America, Australia and Middle East

Recommended Usage

Typical use level 0.01%–0.5% in soothing and anti-acne formulas, depending on grade and target efficacy.

FAQ About Wholesale Licochalcone A

What is the CAS number of Licochalcone A?

CAS 58749-22-7.

What is Licochalcone A?

A chalcone from licorice (Glycyrrhiza inflata) root with anti-inflammatory and anti-acne activity.

What purity grades are available?

HPLC 10%, 30%, 50%, 90%, 95%, 98% available in stock.

Is it water soluble?

It is sparingly soluble in water; soluble in ethanol, methanol and DMSO.

What is the recommended use level?

0.01%–0.5% in soothing and anti-acne formulations.

Is it suitable for acne-prone skin?

Yes — it is known for anti-acne and calming benefits.

Do you provide COA and SDS?

Yes — COA, SDS and heavy metal test reports are available on request.

What is the shelf life?

Typically 24 months stored sealed in a cool, dry place.

Can I get samples?

Yes — trial samples available; terms negotiable with bulk orders.

What are your MOQ terms?

Flexible MOQ, discussed on inquiry.

Start Your Licochalcone A Bulk Order

Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.