Description
Berberine hydrochloride: what it is
Berberine hydrochloride (INCI: Berberine, CAS 633-65-8) is an isoquinoline alkaloid obtained from the roots and bark of Berberis species and from Coptis chinensis. It is supplied as a yellow crystalline powder, standardized to 97% by HPLC, as a raw material for dietary supplement capsules, tablets and blend formulas.
The material is produced by solvent extraction followed by purification and hydrochloride salt formation, then milled to a controlled particle size and packed in light-protected inner liners.
Specifications
| Product name | Berberine Hydrochloride |
| INCI | Berberine |
| CAS number | 633-65-8 |
| Purity | 97% (HPLC), standard grade; other grades on request |
| Appearance | Yellow crystalline powder |
| Assay | By HPLC, the actual result is stated on each batch COA |
| Loss on drying | Reported per batch |
| Heavy metals | Pb, As, Cd, Hg – reported per batch |
| Microbiology | Total plate count, yeast and mould, E. coli, Salmonella – reported per batch |
| Solubility | Slightly soluble in water, soluble in hot water and ethanol |
| Packaging | 1 kg foil bag inside a carton, 25 kg fibre drum |
| Storage | Sealed, away from light and moisture, at ambient temperature |
| Shelf life | 24 months in unopened original packaging |
| MOQ | Subject to the grade and packaging selected |
Where it is used
Berberine hydrochloride is formulated into hard capsules, tablets and multi-ingredient blends. It is also used in cosmetic and personal care formulations where a botanical alkaloid is required.
Quality documentation
Every batch ships with a COA covering assay, heavy metals and microbiological limits. MSDS and TDS are available on request, and third-party testing can be arranged at a nominated laboratory.
Supply and OEM
Bulk supply, private label and OEM capsule or tablet manufacturing are available from the same group, so the raw material and the finished dosage can come from one supply chain. Specification sheets are issued before the first order.
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