Azelaic Acid (CAS 123-99-9) is a naturally occurring dicarboxylic acid found in grains. It combines brightening, anti-inflammatory and anti-acne benefits in a single ingredient — one active, three mechanisms — increasingly used in acne treatments, rosacea management and uneven-tone formulas.
Physical & Chemical Properties
- INCI: Azelaic Acid
- CAS number: 123-99-9
- Appearance: white to off-white crystalline powder
- Solubility: slightly soluble in water; soluble in hot water, ethanol and glycols
- Ionic type: dicarboxylic acid (C9)
- Melting point: approx. 106–109°C
- Source: naturally occurring in grains (wheat, barley)
Key Benefits for Formulation
- Brightening: inhibits tyrosinase and evens skin tone
- Anti-acne: reduces P. acnes and normalizes desquamation
- Anti-inflammatory: soothes redness and supports rosacea management
- Multi-benefit: one ingredient, three mechanisms
- Well tolerated: suitable for sensitive and redness-prone skin
Main Applications
- Acne treatment & blemish products: prescription-style actives
- Rosacea & redness management: anti-inflammatory care
- Brightening & uneven-tone formulas: tyrosinase inhibition
- Combination & oily skin care: sebum regulation
- Post-inflammatory hyperpigmentation (PIH) products
Why Choose Our Bulk Azelaic Acid?
- GMP manufacturing: full quality control from raw material to finished product
- Complete documentation: COA, SDS and heavy metal test reports available on request
- Flexible supply: MOQ and lead time on inquiry, from R&D samples to mass production
- Export experience: reliable shipping to EU, North America, Australia and Middle East
Recommended Usage
Typical use level 5%–15% in leave-on products depending on target efficacy; clinical acne and rosacea products commonly use 10%–15%. Slightly water-soluble — solubilize in hot water, ethanol or glycols for stable formulas. For external use only.
FAQ About Wholesale Azelaic Acid
What is the CAS number of azelaic acid?
CAS 123-99-9.
What is the INCI name?
Azelaic Acid.
Is azelaic acid water soluble?
It is slightly soluble in water and soluble in hot water, ethanol and glycols.
Can azelaic acid brighten skin?
Yes — it inhibits tyrosinase activity, helping to even skin tone and fade post-inflammatory hyperpigmentation.
Is it suitable for rosacea-prone skin?
Its anti-inflammatory properties make it a common choice for redness and rosacea management.
What dosage is recommended?
5%–15% in leave-on products; clinical products commonly use 10%–15%.
What is the melting point?
Approximately 106–109°C.
Start Your Azelaic Acid Bulk Order
Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.