ImaHerb Biotech

Genipin (CAS 6092-77-8): Natural Crosslinking Agent & Bioactive from Gardenia

Genipin (CAS 6092-77-8) is a natural iridoid glucoside aglycone derived from Gardenia jasminoides fruit. It is a biocompatible crosslinking agent for proteins, gelatin and chitosan-based biomaterials, and also functions as an anti-inflammatory bioactive in topical applications.

Physical & Chemical Properties

  • INCI: Genipin
  • CAS number: 6092-77-8
  • Appearance: white to pale yellow crystalline powder
  • Solubility: soluble in water, ethanol, methanol and DMSO
  • Molecular formula: C11H14O5
  • Molecular weight: 226.23
  • Source: Gardenia jasminoides (gardenia) fruit
  • Purity: HPLC ≥98%

Key Benefits for Formulation

  • Biocompatible crosslinking: crosslinks proteins, gelatin and chitosan with low toxicity
  • Natural origin: plant-derived alternative to synthetic crosslinkers
  • Anti-inflammatory: supports soothing topical applications
  • Blue pigment formation: reacts with amino acids to form natural blue pigments
  • Stable supply: consistent purity batch after batch

Main Applications

  • Biomaterials & hydrogels: gelatin/chitosan crosslinking
  • Wound dressings & tissue engineering: biocompatible scaffolds
  • Cosmetics: anti-inflammatory and conditioning actives
  • Functional food & supplement research: gardenia bioactives
  • Natural pigment development: blue color systems

Why Choose Our Bulk Genipin?

  • GMP manufacturing: full quality control from raw material to finished product
  • Complete documentation: COA, SDS and heavy metal test reports available on request
  • Flexible supply: multiple HPLC purity grades in stock, from R&D samples to mass production
  • Export experience: reliable shipping to EU, North America, Australia and Middle East

Recommended Usage

Use level varies by application: 0.1%–1% in topical cosmetics; 0.1%–0.5% (w/w) typical for gelatin/chitosan crosslinking studies. Optimize per system.

FAQ About Wholesale Genipin

What is the CAS number of Genipin?

CAS 6092-77-8.

What is Genipin used for?

Natural biocompatible crosslinking of proteins, gelatin and chitosan, plus anti-inflammatory topical applications.

Is Genipin soluble in water?

Yes — soluble in water, ethanol, methanol and DMSO.

What is the recommended use level?

0.1%–1% in topical cosmetics; 0.1%–0.5% typical for gel crosslinking, depending on system.

Is it from natural sources?

Yes — derived from Gardenia jasminoides fruit.

Does Genipin form blue pigments?

Yes — it reacts with amino acids to form natural blue pigments.

Is it suitable for biomedical use?

It is widely studied as a biocompatible crosslinker; qualification for medical use is the customer’s responsibility.

Do you provide COA and SDS?

Yes — COA, SDS and heavy metal test reports are available on request.

What is the shelf life?

Typically 24 months stored sealed in a cool, dry place.

Can I get samples?

Yes — trial samples available; terms negotiable with bulk orders.

Start Your Genipin Bulk Order

Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.

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