ImaHerb Biotech

R-Alpha Lipoic Acid (R-ALA, CAS 1200-22-2): Natural Antioxidant Form

R-Alpha Lipoic Acid (R-ALA, CAS 1200-22-2) is the naturally occurring, biologically active enantiomer of alpha lipoic acid. Unlike the synthetic racemic mixture, R-ALA is the form the body recognizes and utilizes — offering superior antioxidant and metabolic-support activity at lower doses.

Physical & Chemical Properties

  • CAS number: 1200-22-2
  • Appearance: pale yellow crystalline powder
  • Solubility: slightly soluble in water; soluble in ethanol and oils
  • Molecular formula: C8H14O2S2
  • Molecular weight: 206.33
  • Enantiomeric purity: R-form ≥98% (chiral HPLC)
  • Purity: ≥98%

Key Benefits for Formulation

  • Bioactive enantiomer: the natural R-form, not synthetic racemate
  • Superior bioavailability: effectively utilized at lower doses
  • Antioxidant recycling: regenerates vitamins C & E, glutathione
  • Metabolic support: glucose & energy metabolism cofactor
  • Clean profile: no S-form (which can interfere with uptake)

Main Applications

  • Antioxidant supplements: premium free-radical defense
  • Metabolic health: glucose-support & insulin-sensitivity formulas
  • Anti-aging: mitochondrial support products
  • Neuropathy support: nerve-health applications
  • Sports nutrition: recovery & energy metabolism

Why Choose Our Bulk R-Alpha Lipoic Acid?

  • GMP manufacturing: full quality control from raw material to finished product
  • Complete documentation: COA, SDS and heavy metal test reports available on request
  • Flexible supply: multiple purity grades in stock, from R&D samples to mass production
  • Export experience: reliable shipping to EU, North America, Australia and Middle East

Recommended Usage

Typical use 100–300 mg R-ALA per serving in finished supplements — approximately half the dose of racemic ALA for comparable effect.

FAQ About Wholesale R-Alpha Lipoic Acid

What is the CAS number of R-Alpha Lipoic Acid?

CAS 1200-22-2.

What is R-ALA?

The naturally occurring, biologically active enantiomer of alpha lipoic acid.

How is it different from regular ALA?

Regular ALA is a 50/50 racemic mix; R-ALA is the pure active form.

What is the enantiomeric purity?

R-form ≥98% by chiral HPLC.

What is the typical dose?

100–300 mg per serving.

Is it water soluble?

Slightly soluble in water; soluble in ethanol and oils.

Do you provide COA and SDS?

Yes — full COA, SDS and heavy metal reports available on request.

What is the shelf life?

Typically 24 months stored sealed in a cool, dry place.

Can I get samples?

Yes — trial samples available; terms negotiable with bulk orders.

What are your MOQ terms?

Flexible MOQ, discussed on inquiry.

Start Your R-Alpha Lipoic Acid Bulk Order

Contact our sales team today for spec sheets, samples and bulk pricing — our technical team is ready to support your formulation development.

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